Human Genome Modeled as Ramen?

Someone sent me this article from MIT about how the 3d representation of the human genome ends up looking like uncooked ramen. I only post this here because perhaps one or two readers can actually understand what the heck it’s talking about. I do wish that ramen came in a ball like this too..

“It turns out actually that the fractal globule pretty deeply resembles the model of uncooked ramen noodles,” he said. “You can contrast this with the classic polymer structure, which is the arrangement that the noodles take once you’ve cooked them.”

If you “turn up the heat, and the noodles are going to oscillate and wiggle…and in the process they’ll get deeply, deeply entangled,” he said.

According to Lieberman-Aiden, “this is similar to the classic polymer conformation,” called the “equilibrium globule model.”

In the ramen analog of the equilibrium globule model of the genome, “the most salient property was that if you stick a fork in them, you can’t pull apart one or two noodles: you end up pulling out a whole clump because they are so entangled.”

“The fractal globule module is more like the uncooked ramen, whereas the classic equilibrium model of condensed polymers is more like the cooked noodles,” he said.